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Influenza associated mortality in the subtropics and tropics: Results from three Asian cities.

Identifieur interne : 000B58 ( Main/Exploration ); précédent : 000B57; suivant : 000B59

Influenza associated mortality in the subtropics and tropics: Results from three Asian cities.

Auteurs : Lin Yang [République populaire de Chine] ; Stefan Ma [Singapour] ; Ping Yan Chen [République populaire de Chine] ; Jian Feng He [République populaire de Chine] ; King Pan Chan [République populaire de Chine] ; Angela Chow [Singapour] ; Chun Quan Ou [République populaire de Chine] ; Ai Ping Deng [République populaire de Chine] ; Anthony J. Hedley ; Chit Ming Wong [République populaire de Chine] ; J S Malik Peiris [Hong Kong]

Source :

RBID : Hal:pasteur-00639817

Abstract

Influenza has been well documented to significantly contribute to winter increase of mortality in the temperate countries, but its severity in the subtropics and tropics was not recognized until recently and geographical variations of disease burden in these regions remain poorly understood. In this study, we applied a standardized modeling strategy to the mortality and virology data from three Asian cities: subtropical Guangzhou and Hong Kong, and tropical Singapore, to estimate the disease burden of influenza in these cities. We found that influenza was associated with 10.6, 13.4 and 8.3 deaths per 100,000 population in Guangzhou, Hong Kong and Singapore, respectively. The annual rates of excess deaths in the elders were estimated highest in Guangzhou and lowest in Singapore. The excess death rate attributable to A/H1N1 subtype was found slightly higher than the rates attributable to A/H3N2 during the study period of 2004-2006 based on the data from Hong Kong and Guangzhou. Our study revealed a geographical variation in the disease burden of influenza in these subtropical and tropical cities. These results highlight a need to explore the determinants for severity of seasonal influenza.


Url:
DOI: 10.1016/j.vaccine.2011.09.071


Affiliations:


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<org type="regroupinstitution" xml:id="struct-301247" status="VALID">
<orgName>Réseau International des Instituts Pasteur</orgName>
<orgName type="acronym">RIIP</orgName>
<desc>
<address>
<addrLine>25, rue du Dr Roux 75724 Paris Cedex 15</addrLine>
<country key="FR"></country>
</address>
<ref type="url">https://research.pasteur.fr/ip-network</ref>
</desc>
</org>
</tutelle>
</tutelles>
</hal:affiliation>
<country>Hong Kong</country>
</affiliation>
</author>
</analytic>
<idno type="DOI">10.1016/j.vaccine.2011.09.071</idno>
<series>
<title level="j">Vaccine</title>
<idno type="ISSN">0264-410X</idno>
<imprint>
<date type="datePub">2011-11-08</date>
</imprint>
</series>
</biblStruct>
</sourceDesc>
</fileDesc>
<profileDesc>
<textClass></textClass>
</profileDesc>
</teiHeader>
<front>
<div type="abstract" xml:lang="en">
<p>Influenza has been well documented to significantly contribute to winter increase of mortality in the temperate countries, but its severity in the subtropics and tropics was not recognized until recently and geographical variations of disease burden in these regions remain poorly understood. In this study, we applied a standardized modeling strategy to the mortality and virology data from three Asian cities: subtropical Guangzhou and Hong Kong, and tropical Singapore, to estimate the disease burden of influenza in these cities. We found that influenza was associated with 10.6, 13.4 and 8.3 deaths per 100,000 population in Guangzhou, Hong Kong and Singapore, respectively. The annual rates of excess deaths in the elders were estimated highest in Guangzhou and lowest in Singapore. The excess death rate attributable to A/H1N1 subtype was found slightly higher than the rates attributable to A/H3N2 during the study period of 2004-2006 based on the data from Hong Kong and Guangzhou. Our study revealed a geographical variation in the disease burden of influenza in these subtropical and tropical cities. These results highlight a need to explore the determinants for severity of seasonal influenza.</p>
</div>
</front>
</TEI>
<affiliations>
<list>
<country>
<li>Hong Kong</li>
<li>République populaire de Chine</li>
<li>Singapour</li>
</country>
</list>
<tree>
<noCountry>
<name sortKey="Hedley, Anthony J" sort="Hedley, Anthony J" uniqKey="Hedley A" first="Anthony J" last="Hedley">Anthony J. Hedley</name>
</noCountry>
<country name="République populaire de Chine">
<noRegion>
<name sortKey="Yang, Lin" sort="Yang, Lin" uniqKey="Yang L" first="Lin" last="Yang">Lin Yang</name>
</noRegion>
<name sortKey="Chan, King Pan" sort="Chan, King Pan" uniqKey="Chan K" first="King Pan" last="Chan">King Pan Chan</name>
<name sortKey="Chen, Ping Yan" sort="Chen, Ping Yan" uniqKey="Chen P" first="Ping Yan" last="Chen">Ping Yan Chen</name>
<name sortKey="Deng, Ai Ping" sort="Deng, Ai Ping" uniqKey="Deng A" first="Ai Ping" last="Deng">Ai Ping Deng</name>
<name sortKey="He, Jian Feng" sort="He, Jian Feng" uniqKey="He J" first="Jian Feng" last="He">Jian Feng He</name>
<name sortKey="Ou, Chun Quan" sort="Ou, Chun Quan" uniqKey="Ou C" first="Chun Quan" last="Ou">Chun Quan Ou</name>
<name sortKey="Wong, Chit Ming" sort="Wong, Chit Ming" uniqKey="Wong C" first="Chit Ming" last="Wong">Chit Ming Wong</name>
</country>
<country name="Singapour">
<noRegion>
<name sortKey="Ma, Stefan" sort="Ma, Stefan" uniqKey="Ma S" first="Stefan" last="Ma">Stefan Ma</name>
</noRegion>
<name sortKey="Chow, Angela" sort="Chow, Angela" uniqKey="Chow A" first="Angela" last="Chow">Angela Chow</name>
</country>
<country name="Hong Kong">
<noRegion>
<name sortKey="Peiris, J S Malik" sort="Peiris, J S Malik" uniqKey="Peiris J" first="J S Malik" last="Peiris">J S Malik Peiris</name>
</noRegion>
</country>
</tree>
</affiliations>
</record>

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